AHRQ Awards $8.9 Million Grant to PRIS and CHCA for New Database to Measure Comparative Effectiveness
September 12, 2010
Posted by chcablogadmin in : Academic Medicine, Innovation, Quality
We are extremely excited about receiving the AHRQ grant and continuing our successful collaboration with the PRIS network. Dr. Ron Keren of the Children’s Hospital of Philadelphia describes the project and the relationship with CHCA. This is an amazing affirmation of our Owner Hospitals’ leadership in the improvement and data arena. – Don
The Agency for Healthcare Research and Quality has awarded the Pediatric Research in Inpatient Settings (PRIS) network and CHCA a three-year, $8.9 million grant to create an infrastructure for comparative effectiveness research. Specifically, the project will augment PHIS with laboratory and radiology results from six children’s hospitals across multiple sites of care—inpatient, outpatient, emergency department and day surgery. This new combined clinical and administrative data will be called “PHIS+.” Researchers will then be able to generate new high quality evidence on the comparative effectiveness of health care interventions for hospitalized children.
Ron Keren, M.D., MPH
“The addition of clinical data, such as laboratory, microbiology, and radiology results, will significantly expand the scope of questions and outcomes that pediatric researchers will be able to study. CHCA is in a unique position to disseminate the results of the comparative effectiveness research projects that will result from the AHRQ grant. PRIS investigators hope that the PHIS+ database will be used to measure quality of care, and CHCA can play a role in organizing quality improvement collaboratives that utilize the PHIS+ data,” said Principal Investigator Ron Keren, M.D, MPH, Associate Professor of Pediatrics and Director of the Center for Pediatric Clinical Effectiveness, Children’s Hospital of Philadelphia.
CHCA will receive $1.2 million to develop the database and for support of the research efforts to follow. The first 18 months of the project to begin Sept. 30 will be spent on creating the database, the infrastructure to support it, and collecting data from the six participating hospitals. The second 18 months will be spent researching the data for several proposed comparative effectiveness projects.
Dr. Keren described the relationship between the PRIS network and CHCA. ”The PRIS co-investigators working on the PHIS+ project have a long history of working with CHCA staff to conduct comparative effectiveness research,” he stated. “Collectively, they have published 19 research papers using the PHIS database and 9 more papers are currently under review with scientific journals.”
According to Dr. Keren, the PHIS+ project will build the data platform for hospitals to make advances in the following areas:
- Make the most efficient use of their diagnostic armamentarium (i.e. laboratory testing and imaging studies) to predict outcomes, select appropriate interventions, and improve the health status of children;
- Apply state-of-the-art observational study design and analysis to existing data in administrative and clinical databases to evaluate therapeutic, prognostic, and diagnostic strategies for conditions for which randomized controlled trials are not feasible;
- Perform economic evaluations of inpatient management strategies to inform resource allocation and, coupled with outcomes measurement, better understand value; and
- Develop quality measures and severity adjustment tools to study inpatient quality (comparing hospitals, providers, systems) across multiple institutions using large administrative and clinical databases.
The project team will also be looking at whether the database can be rolled out to all CHCA Owner Hospitals in a cost effective way. The six hospitals participating are Children’s Hospital of Philadelphia, Primary Children’s Hospital/Salt Lake City, Children’s Hospital Boston, Cincinnati Children’s Medical Center, Seattle Children’s Hospital and Pittsburgh Children’s Hospital.
If you have any questions, please contact Matt Hall(matt.hall@chca.com), one of the CHCA principal investigators on the project.
Comments»
no comments yet - be the first?